ARG82240
Mouse TLR1 ELISA Kit
Mouse TLR1 ELISA Kit for ELISA and Mouse
Overview
| Product Description | ARG82240 Mouse TLR1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse TLR1 in serum and plasma. |
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| Tested Reactivity | Ms |
| Tested Application | ELISA |
| Specificity | The following recombinant Mouse proteins were tested and exhibited no cross-reactivity or interference: IL1 beta, IL2, IL4, IL5, IL6, IL8, IL10, IL15, IFN gamma, TLR2, TLR3, TLR4, TNF alpha. |
| Target Name | TLR1 |
| Conjugation Note | Read at 450 nm. |
| Sensitivity | 47 pg/ml |
| Sample Type | Serum and plasma. |
| Standard Range | 94 - 6000 pg/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: 6% Inter-Assay CV: 11% |
| Alternate Names | CD281; CD antigen CD281; Toll/interleukin-1 receptor-like protein; TIL; Toll-like receptor 1; rsc786; TIL. LPRS5 |
Application Instructions
| Assay Time | 3 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
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| Gene Symbol | TLR1 |
| Gene Full Name | toll-like receptor 1 |
| Background | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008] |
| Function | Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). [UniProt] |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. Membrane raft. Golgi apparatus. Note=Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to triacylated lipoproteins, TLR2:TLR1 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus. [UniProt] |
| Highlight | Related products: TLR1 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Title | Download Link |
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| ARG82240 Mouse TLR1 ELISA Kit User manual |
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