ARG81181

Mouse TSLP ELISA Kit

Mouse TSLP ELISA Kit for ELISA and Mouse

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Overview

Product Description

ARG81181 Mouse TSLP ELISA Kit is an Enzyme Immunoassay Kit for the quantification of Mouse TSLP in serum, plasma and cell culture supernatants.

Tested Reactivity Ms
Tested Application ELISA
Specificity No significant cross-reactivity or interference with Mouse IL-7, TSLP R/Fc Chimera and Human TSLP, TSLP R/Fc Chimera.
Target Name TSLP
Conjugation HRP
Conjugation Note

Substrate: TMB and read at 450 nm

Sensitivity 15 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 31.25 - 2000 pg/ml
Sample Volume 100 µl
Alternate Names Thymic stromal lymphopoietin

Application Instructions

Assay Time ~ 3.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 53603 Mouse TSLP

Swiss-port # Q9JIE6 Mouse Thymic stromal lymphopoietin

Gene Symbol Tslp
Gene Full Name thymic stromal lymphopoietin
Background This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Function Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.

Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. [UniProt]
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Specific References

Hollow manganese dioxide-chitosan hydrogel for the treatment of atopic dermatitis through inflammation-suppression and ROS scavenging

ELISA / Mouse / Serum

Yaguang Wu et al.
J Nanobiotechnology.,  (2023)

publication_link

 

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