ARG30251

NFkB nuclear translocation Antibody Panel

Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Controls and Markers antibody; Gene Regulation antibody; Immune System antibody; Metabolism antibody; Microbiology and Infectious Disease antibody; Neuroscience antibody; Signaling Transduction antibody
publication_link Publication14

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG10112 anti-GAPDH antibody [6C5] Mouse mAb AGMK, Bb, Cat, Chk, Dog, Fsh, Hm, Hu, Mk, Ms, Pig, Rb, Rat, Xenopus laevis, Zfsh ELISA, ICC/IF, IHC-Fr, WB 50 μg
ARG54747 anti-Histone H3 antibody Mouse mAb Hu WB 100 μl
ARG54746 anti-NFkB p105 / p50 antibody Mouse mAb Hu FACS, IHC-P, WB 100 μl
ARG51013 anti-NFkB p65 antibody Rabbit pAb Hu, Ms, Rat IHC-P, WB 50 μl
ARG65350 Goat anti-Mouse IgG antibody (HRP) Goat pAb Ms ELISA, IHC-P, WB 50 μl

Overview

Product Description Nuclear factor kappa B (NFkB) is a protein complex that controls large number of genes responsible for the regulation of apoptosis, inflammation, tumorigenesis and a variety of immune responses. NF-kB is sensitive and responsive to stimuli such as cytokines, stress, UV, low oxygen, bacterial or viral infections. Upon activation, NFkB is translocated into nucleus and exert its function on the transcriptional regulation of NFkB-responsive genes. Histone H3 is a marker for nuclear fraction while GAPDH is a marker for cytosolic fraction.

Baeuerle et al. 1991. Biochem Biophys Acta 1072: 63-80
Lenardo and Baltimore. 1989. Cell 58: 227
Target Name NFkB nuclear translocation
Alternate Names NFkB nuclear translocation antibody; GAPDH antibody; NFkB p65 antibody; NFkB p105 / p50 antibody; Histone H3 antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name Antibody Panel for NFkB nuclear translocation
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Controls and Markers antibody; Gene Regulation antibody; Immune System antibody; Metabolism antibody; Microbiology and Infectious Disease antibody; Neuroscience antibody; Signaling Transduction antibody

Specific References

KDF1 Promoted Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells through Activating STAT3 and AKT Pathway

ARG65350: WB / 

Yi-Qing Guo et al.
Biomedicines.,  (2023)

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PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis

ARG10112: WB / Rat

Xiang Xue et al.
J Orthop Surg Res.,  (2023)

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hr_line

Uric acid mitigates cognitive deficits via transcription factor EB - mediated microglial autophagy in mice models of Alzheimer's disease

ARG10112: WB / Mouse

Qian Xiao et al.
,  (2023)

publication_link

 

hr_line

Knockdown of Porf-2 restores visual function after optic nerve crush injury

ARG10112: WB / Mouse

Di Chen et al.
Cell Death Dis.,  (2023)

publication_link

 

hr_line

黄芪甲苷预处理对大鼠肠缺血再灌注所致肺损伤的影响及其机制

ARG10112: WB / Rat

王蕾 et al.
中国中西医结合外科杂志,  (2023)

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Thalidomide Alleviates Pulmonary Fibrosis Induced by Silica in Mice by Inhibiting ER Stress and the TLR4-NF-κB Pathway

ARG51013: WB / Mouse

Yaqian Li et al.
International Journal of Molecular Sciences,  (2022)

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hr_line

Reproductive toxicity investigation of silica nanoparticles in male pubertal mice

ARG51013: WB / Mouse

Fanli Sun et al.
Environ Sci Pollut Res Int.,  (2022)

publication_link

 

hr_line

Downregulation of lncRNA NEAT1 alleviates sepsis-induced acute kidney injury

ARG10112: WB / Human

Yuhua Zhou et al.
Cent Eur J Immunol .,  (2022)

publication_link

 

hr_line

Toxicity Investigation of Nano-SiO2 on Male Reproductive System in Pubertal Mice

ARG51013: WB / Mouse

Fanli Sun et al.
Research Square,  (2021)

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hr_line

Cardiac-Specific Gene TNNI3 as a Potential Oncogene for Kidney Cancer and Its Involvement in Wnt Signaling Pathway.

ARG10112: WB / Human

Weian Zhao et al.
Preprint.,  (2021)

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Mesenchymal Stem Cell-Derived Exosomes Ameliorate Alzheimer's Disease Pathology and Improve Cognitive Deficits.

ARG10112: WB / Human

Yi-An Chen et al.
Biomedicines.,  (2021)

publication_link

 

hr_line

Ac-SDKP Attenuates Activation of Lung Macrophages and Bone Osteoclasts in Rats Exposed to Silica by Inhibition of TLR4 and RANKL Signaling Pathways.

ARG51013: WB / Rat

Fuyu Jin et al.
J Inflamm Res.,  (2021)

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hr_line

Evaluation of Class IIa Histone Deacetylases Expression and In Vivo Epigenetic Imaging in a Transgenic Mouse Model of Alzheimer's Disease

ARG10112: WB / Human

Yi-An Chen et al.
Int J Mol Sci.,  (2021)

publication_link

 

hr_line

Circ_0081572 inhibits the progression of periodontitis through regulating the miR-378h/RORA axis.

ARG10112: WB / Human

Jing Wang et al.
Arch Oral Biol.,  (2021)

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