ARG80934

Neuropeptide Y ELISA Kit

Neuropeptide Y ELISA Kit for ELISA and Human,Mouse,Pig,Rat

Cell Biology and Cellular Response kit; Metabolism kit; Neuroscience kit
publication_link Publication1

Overview

Product Description ARG80934 Neuropeptide Y ELISA Kit is an Enzyme Immunoassay kit for the quantification of Neuropeptide Y in blood collection, serum, plasma extraction, tissue extraction and CSF extraction.
Tested Reactivity Hu, Ms, Rat, Pig
Tested Application ELISA
Specificity Cross reactivity:
Neuropeptide Y (Human, Rat, Mouse): 100%
Neuropeptide Y (Pig): 100%
Neuropeptide Y (3-36) (Human, Rat, Mouse): 14.3%
Peptide YY (Human): 0%
Peptide YY (Rat, Mouse, Porcine, Canine): 0%
Pancreatic Polypeptide (Human): 0%
VIP (Human, Rat, Porcine): 0%
Insulin (Human): 0%
Amylin (Human): 0%
Somatostatin (Human, Rat, Mouse, Porcine): 0%
Target Name Neuropeptide Y
Sensitivity 0.09 ng/ml
Detection Range 0 - 100 ng/ml; linear range: 0.09 - 1.75 ng/ml
Sample Type Blood collection, serum, plasma extraction, tissue extraction and CSF extraction.
Standard Range 0 - 100 ng/ml
Alternate Names Pro-neuropeptide Y; Neuropeptide tyrosine; NPY; CPON; PYY4

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol NPY
Gene Full Name neuropeptide Y
Background NPY gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
Function NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. [UniProt]
Highlight Related products:
Neuropeptide antibodies; Neuropeptide ELISA Kits;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
Research Area Cell Biology and Cellular Response kit; Metabolism kit; Neuroscience kit
PTM The neuropeptide Y form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro).

Specific References

Behavioral changes and brain epigenetic alterations induced by maternal deficiencies of B vitamins in a mouse model.

ELISA / Mouse / Serum

Pei Xu et al.
Psychopharmacology (Berl).,  (2021)

publication_link

 

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