ARG30267

Organelle Marker, Cytoplasm, Nucleus Antibody Duo (Histone, GAPDH)

publication_link Publication21

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG65681 anti-Histone H3 antibody Mouse mAb Hu, Ms, Rat ICC/IF, IHC-P, IP, WB 50 μg
ARG10112 anti-GAPDH antibody [6C5] Mouse mAb AGMK, Bb, Cat, Chk, Dog, Fsh, Hm, Hu, Mk, Ms, Pig, Rb, Rat, Xenopus laevis, Zfsh ELISA, ICC/IF, IHC-Fr, WB 50 μg

Overview

Product Description

GAPDH is often stably and constitutively expressed at high levels in most tissues and cells in cytoplasm. Therefore, GAPDH is a widely used loading control and cytoplasm marker for western blotting (35-40kDa) and Immunostaining study.

Histone H3 (15-20kDa) is one of the component of nucleosomes in nucleus. So Histone H3 is one of the commonly used loading control and nucleus marker in western blotting and Immunostaining study.

This Cytoplasm, Nucleus antibody Duos not only provide different MW targets for internal control selection, but also provide cytoplasm (GAPDH) and nucleus (Histone H3) markers to control the quality of cytoplasm and nucleus fractions after subcellular fractionation process and to identify the cytoplasm and nucleus position in Immunostaining study.

Target Name Organelle Marker, Cytoplasm, Nucleus
Alternate Names Organelle Marker, Cytoplasm, Nucleus antibody; GAPDH antibody; Histone H3 antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Specific References

Uric acid mitigates cognitive deficits via transcription factor EB - mediated microglial autophagy in mice models of Alzheimer's disease

ARG10112: WB / Mouse

Qian Xiao et al.
,  (2023)

publication_link

 

hr_line

黄芪甲苷预处理对大鼠肠缺血再灌注所致肺损伤的影响及其机制

ARG10112: WB / Rat

王蕾 et al.
中国中西医结合外科杂志,  (2023)

publication_link

 

hr_line

PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis

ARG10112: WB / Rat

Xiang Xue et al.
J Orthop Surg Res.,  (2023)

publication_link

 

hr_line

Knockdown of Porf-2 restores visual function after optic nerve crush injury

ARG10112: WB / Mouse

Di Chen et al.
Cell Death Dis.,  (2023)

publication_link

 

hr_line

Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation

ARG65681: IHC-P / Mouse

Zhenyu Tian et al.
Cell Host Microbe,  (2022)

publication_link

 

hr_line

SCM-198 Prevents Endometriosis by Reversing Low Autophagy of Endometrial Stromal Cell via Balancing ERα and PR Signals

ARG10112: WB / Mouse

Yi-Kong Lin  et al.
Front Endocrinol (Lausanne),  (2022)

publication_link

 

hr_line

Pharmacological inhibition of SMYD2 protects against cisplatin-induced acute kidney injury in mice

ARG10112: WB / Mouse

Binbin Cui  et al.
Front Pharmacol,  (2022)

publication_link

 

hr_line

Lack of interferon regulatory factor 3 leads to anxiety/depression-like behaviors through disrupting the balance of neuronal excitation and inhibition in mice

ARG10112: WB / Mouse

Junjie Li et al.
Genes & Diseases,  (2022)

publication_link

 

hr_line

Mesenchymal Stem Cells-Derived Exosomes Ameliorate Ischemia/Reperfusion Induced Acute Kidney Injury in a Porcine Model

ARG10112: WB / Pig

Jianni Huang et al.
Frontiers in Cell and Developmental Biology,  (2022)

publication_link

 

hr_line

Genetic labeling reveals cellular expression pattern of neuregulin 1 in mouse forebrain

ARG10112: WB / Human

Chen-Yun Ding et al.
Research square,  (2022)

publication_link

 

hr_line

Downregulation of lncRNA NEAT1 alleviates sepsis-induced acute kidney injury

ARG10112: WB / Human

Yuhua Zhou et al.
Cent Eur J Immunol .,  (2022)

publication_link

 

hr_line

Qi-Tai-Suan, an oleanolic acid derivative, ameliorates ischemic heart failure via suppression of cardiac apoptosis, inflammation and fibrosis

ARG10112: WB / Human

QIAN Ming et al.
 Chinese Journal of Natural Medicines ,  (2022)

publication_link

 

hr_line

Evaluation of Class IIa Histone Deacetylases Expression and In Vivo Epigenetic Imaging in a Transgenic Mouse Model of Alzheimer's Disease

ARG10112: WB / Human

Yi-An Chen et al.
Int J Mol Sci.,  (2021)

publication_link

 

hr_line

The Phosphorylation Status of Drp1-Ser637 by PKA in Mitochondrial Fission Modulates Mitophagy via PINK1/Parkin to Exert Multipolar Spindles Assembly during Mitosis.

ARG10112: WB / Human

Huey-Jiun Ko et al.
Biomolecules.,  (2021)

publication_link

 

hr_line

Curcumin attenuates renal ischemia reperfusion injury via JNK pathway with the involvement of p300/CBP-mediated histone acetylation

ARG10112: WB / Rat

Lu Yang et al.
Korean J Physiol Pharmacol.,  (2021)

publication_link

 

hr_line

M351-0056 is a novel low MW compound modulating the actions of the immune-checkpoint protein VISTA.

ARG10112: WB / Human, Mouse

Xinlei Hu et al.
Br J Pharmacol.,  (2021)

publication_link

 

hr_line

7,8-dihydroxyflavone ameliorates motor deficits via regulating autophagy in MPTP-induced mouse model of Parkinson's disease

ARG10112: WB / Mouse

Li Zuo et al.
Cell Death Discov.,  (2021)

publication_link

 

hr_line

Cardiac-Specific Gene TNNI3 as a Potential Oncogene for Kidney Cancer and Its Involvement in Wnt Signaling Pathway.

ARG10112: WB / Human

Weian Zhao et al.
Preprint.,  (2021)

publication_link

 

hr_line

Mesenchymal Stem Cell-Derived Exosomes Ameliorate Alzheimer's Disease Pathology and Improve Cognitive Deficits.

ARG10112: WB / Human

Yi-An Chen et al.
Biomedicines.,  (2021)

publication_link

 

hr_line

Circ_0081572 inhibits the progression of periodontitis through regulating the miR-378h/RORA axis.

ARG10112: WB / Human

Jing Wang et al.
Arch Oral Biol.,  (2021)

publication_link

 

hr_line

Structural Basis of VSIG3: The Ligand for VISTA.

ARG10112: WB / Human

Xiaoxue Xie et al.
Front Immunol.,  (2021)

publication_link

 

hr_line