ARG82188
Peroxidase Activity Assay Kit (Colorimetric)
Peroxidase Activity Assay Kit (Colorimetric) for Functional study and Human,Mouse,Rat,All species
Overview
| Product Description | ARG82188 Peroxidase Activity Assay Kit (Colorimetric) can be used to measure Peroxidase activity in serum, plasma, urine, tissue and cell culture supernatants. |
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| Tested Reactivity | Hu, Ms, Rat, All |
| Tested Application | FuncSt |
| Target Name | Peroxidase |
| Conjugation Note | Read at 570 nm (colorimetric), or 530/585 nm (fluorometric) |
| Sensitivity | 4 U/L (colorimetric); 0.8 U/L (fluorometric) |
| Detection Range | 2 - 50 U/L (colorimetric); 0.1 - 5 U/L (fluorometric) |
| Sample Type | serum, plasma, urine, tissue and cell culture supernatants |
| Sample Volume | 10 µl |
| Alternate Names | TPO; EC 1.11.1.8; TDH2A; Thyroid peroxidase; MSA; TPX |
Application Instructions
| Application Note | Please note that this kit does not include a microplate. |
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| Assay Time | 20 min |
Properties
| Form | Liquid |
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| Storage Instruction | Store the kit at -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TPO |
| Gene Full Name | thyroid peroxidase |
| Background | This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011] |
| Function | Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). [UniProt] |
| Cellular Localization | Membrane; Single-pass type I membrane protein. Isoform 3: Cell surface. [UniProt] |
| PTM | Glycosylated. Heme is covalently bound through a H(2)O(2)-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface. Cleaved in its N-terminal part. [UniProt] |
| Title | Download Link |
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| ARG82188 Peroxidase Activity Assay Kit (Colorimetric) User manual |
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