ARG30024

Phospho CREB (pS133) / Phospho beta Catenin (pS37) Antibody Duo

Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody; Gene Regulation antibody; Immune System antibody; Neuroscience antibody; Signaling Transduction antibody

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG51556 anti-CREB phospho (Ser133) antibody Rabbit pAb Hu, Ms, Rat IHC-P, WB 50 μl
ARG51710 anti-beta Catenin phospho (Ser37) antibody Rabbit pAb Hu, Ms, Rat WB, IHC-P 50 μl

Overview

Product Description

Constitutively active GSK-3 acts to destabilize beta catenin through phosphorylation (Ser37), thus, functioning as a tumor suppressor to limit proliferation. In contrast, GSK-3 promotes expansion of leukemic cells transformed by HOX overexpression through phosphorylation of CREB (Ser133) and subsequent formation of a transcriptional coactivator complex. (Cancer Cell 17, June 15, 2010)



Arigo provide CREB / beta Catenin phospho Duos, ARG30024, which include beta catenin (phosphor Ser37) antibody and CREB (phosphor Ser133) antibody for researchers to analysis the downstream protein and the pathway of active-GSK-3

Target Name CREB / beta Catenin
Alternate Names Phospho CREB (pS133) / Phospho beta Catenin (pS37) antibody; Phospho cAMP responsive element binding protein (pS133) / Phospho beta Catenin (pS37) antibody; CREB phospho (Ser133) antibody; beta Catenin phospho (Ser37) antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name Phospho cAMP responsive element binding protein (CREB) (pS133) / Phospho beta Catenin (pS37) Antibody Duo
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody; Gene Regulation antibody; Immune System antibody; Neuroscience antibody; Signaling Transduction antibody