ARG30157

Phospho CaMKII Antibody Duo

Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG64934 anti-CaMKII alpha antibody Goat pAb Hu, Ms, Rat FACS, ICC/IF, WB 50 μg
ARG51767 anti-CaMKII phospho (Thr286) antibody Rabbit pAb Hu, Ms, Rat WB 50 μl

Overview

Product Description CaMKII is an important member of the calcium/calmodulin-activated protein kinase family, functioning in neural synaptic stimulation and T cell receptor signaling. CaMKII has catalytic and regulatory domains. Ca2+/calmodulin binding to the CaMKII regulatory domain relieves autoinhibition and activates the kinase. The activated CaMKII further autophosphorylates at Thr286 to render the kinase constitutively active. Hughes, K. et al. (2001) J Biol Chem 276, 36008-13. Barria, A. et al. (1997) Science 276, 2042-2045. Barkai, U. et al. (2000) Mol. Endocrinol. 14, 554-563.
Target Name CaMKII
Alternate Names Phospho CaMKII antibody; Phospho Calcium / calmodulin dependent protein kinase II antibody; CaMKII phospho (Thr286) antibody; CaMKII alpha antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name Phospho Calcium / calmodulin dependent protein kinase II (CaMKII) Antibody Duo
Research Area Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody