ARG30231

Phospho Ezrin Antibody Duo (Total, pT567)

Cancer antibody; Signaling Transduction antibody

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG51694 anti-Ezrin phospho (Thr567) antibody Rabbit pAb Hu, Ms, Rat WB 50 μl
ARG63968 anti-Ezrin antibody Goat pAb Hu IHC-P, WB 50 μg

Overview

Product Description Ezrin, also known as cytovillin or villin-2, belongs to ERM protein family that serves as intermediate between the plasma membrane and the actin cytoskeleton. It plays a key role in cell surface structure adhesion, migration, and organization. Phosphorylation of Ezrin has been functionally linked to acid secretion and vesicle recruitment to the apical secretory membrane in gastric parietal cells. Phosphorylation of the conserved T567 residue of ezrin has been shown to alter the N/C oligomerization of Ezrin and promote the formation of actin-rich surface projections in other cells. Zhu et al. 2007. Am J Physiol Cell Physiol 283(3): 874 Zhou et al. 2005. J Cell Sci 118: 4381
Target Name Ezrin
Alternate Names Phospho Ezrin antibody; Ezrin phospho (Thr567) antibody; Ezrin antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name Phospho Ezrin Antibody Duo (Total, pT567)
Research Area Cancer antibody; Signaling Transduction antibody