ARG30230
Phospho Integrin beta 3 Antibody Panel (Total, pY773, pY785)
Cancer antibody; Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody
Publication1
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG51564 | anti-CD61 / Integrin beta 3 phospho (Tyr773) antibody | Rabbit pAb | Hu, Ms | WB, IHC-P | 50 μl |
| ARG51763 | anti-CD61 / Integrin beta 3 phospho (Tyr785) antibody | Rabbit pAb | Hu, Ms | WB | 50 μl |
| ARG54044 | anti-CD61 / Integrin beta 3 antibody (N-term) | Mouse mAb | Hu | WB | 50 μl |
| ARG65350 | Goat anti-Mouse IgG antibody (HRP) | Goat pAb | Ms | ELISA, IHC-P, WB | 50 μl |
| ARG65351 | Goat anti-Rabbit IgG antibody (HRP) | Goat pAb | Rb | ELISA, IHC-P, WB | 50 μl |
Overview
| Product Description | Cells recognize and respond to their extracellular environment through transmembrane receptors such as integrins, which physically connect the extracellular matrix to the cytoskeleton. Integrins provide the basis for the assembly of intracellular signaling platforms that link to the cytoskeleton and influence nearly every aspect of cell physiology. The integrin beta 3 protein mediates platelet adhesion to immobilized fibrinogen. Adhesion to fibrinogen induced rapid phosphorylation of Integrin beta 3 on Tyr773 and Tyr785 residues, which was reduced by Nitrogen Oxide in a cGMP independent manner. Oberprieler et al. 2007. FEBS Lett 581(7) Legate and Fassler. J Cell Sci 122: 187-98 |
|---|---|
| Target Name | Integrin beta 3 |
| Alternate Names | Phospho Integrin beta 3 antibody; CD61 / Integrin beta 3 phospho (Tyr773) antibody; CD61 / Integrin beta 3 phospho (Tyr785) antibody; CD61 / Integrin beta 3 antibody (N-term) |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | Antibody Panel for Phospho Integrin beta 3 (Total, pY773, pY785) |
|---|---|
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody |
Specific References
KDF1 Promoted Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells through Activating STAT3 and AKT Pathway
ARG65350: WB /
