ARG30170
Phospho Src Antibody Panel
Cancer antibody; Gene Regulation antibody; Immune System antibody; Metabolism antibody; Signaling Transduction antibody
Publication1
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG54712 | anti-Src antibody | Mouse mAb | Hu, Ms | ICC/IF, WB | 100 μl |
| ARG51594 | anti-Src phospho (Tyr418) antibody | Rabbit pAb | Hu, Ms, Rat | WB, IHC-P | 50 μl |
| ARG51652 | anti-Src phospho (Tyr529) antibody | Rabbit pAb | Hu, Ms, Rat | WB, IHC-P, ICC/IF | 50 μl |
| ARG65350 | Goat anti-Mouse IgG antibody (HRP) | Goat pAb | Ms | ELISA, IHC-P, WB | 50 μl |
| ARG65351 | Goat anti-Rabbit IgG antibody (HRP) | Goat pAb | Rb | ELISA, IHC-P, WB | 50 μl |
Overview
| Product Description | Src and Src-family protein-tyrosine kinases are regulatory proteins that play key roles in cell differentiation, motility, proliferation, and survival. The initially described phosphorylation sites of Src include an activating phosphotyrosine 418 that results from autophosphorylation, and an inhibiting phosphotyrosine 529 that results from phosphorylation by C-terminal Src kinase (Csk) and Csk homologous kinase. Dephosphorylation of phosphotyrosine 529 increases Src kinase activity. This antibody panel can be used for determine the activity of Src by different specific phosphorylation site. Wu S.S. et al. (2005) Cellular Signalling 17, 93-102. Obergfell A. et al. (2002) JCB 157, 265-275. Zhao M. et al. (2006) Mol. Cell. Biol. 26, 2479-2489. |
|---|---|
| Target Name | Src |
| Alternate Names | Phospho Src antibody; Src phospho (Tyr418) antibody; Src phospho (Tyr529) antibody; Src antibody |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | Antibody Panel for Phospho Src |
|---|---|
| Research Area | Cancer antibody; Gene Regulation antibody; Immune System antibody; Metabolism antibody; Signaling Transduction antibody |
Specific References
KDF1 Promoted Proliferation, Migration and Invasion of Lung Adenocarcinoma Cells through Activating STAT3 and AKT Pathway
ARG65350: WB /
