ARG30202

Phospho p70 S6 Kinase Antibody Duo (Total, pS411)

Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG51236 anti-p70 S6 Kinase antibody Rabbit pAb Hu, Ms, Rat ICC/IF, IHC-P, WB 50 μl
ARG51753 anti-p70 S6 Kinase phospho (Ser411) antibody Rabbit pAb Hu, Ms, Rat ICC/IF, IHC-P, WB 50 μl

Overview

Product Description

p70S6 Kinase phosphorylates specifically ribosomal protein S6 in response to Insulin or several classes of mitogens. It has been shown to be required for cell growth, cell cycle progression and is involved in translational control mechanism. p70S6K can be phosphorylated by Ang II at the Ser-411 site and the phosphorylation appear to involve EGF receptor transactivation and inhibited by dominant-negative Ras. Dufner, A. and Thomas, G. (1999) Exp Cell Res 253, 100-9. Eguchi, S. (1999) JBC(274): 36843-51

Target Name p70 S6 Kinase
Alternate Names Phospho p70 S6 Kinase antibody; p70 S6 Kinase antibody; p70 S6 Kinase phospho (Ser411) antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name Antibody Duo for Phospho p70 S6 Kinase (Total, pS411)
Research Area Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody