ARG81128
Rat Atrial Natriuretic Peptide (ANP) ELISA Kit
Rat Atrial Natriuretic Peptide (ANP) ELISA Kit for ELISA and Rat
Overview
| Product Description | ARG81128 Rat Atrial Natriuretic Peptide (ANP) ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rat Atrial Natriuretic Peptide in serum, plasma, cell culture and tissue extract. |
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| Tested Reactivity | Rat |
| Tested Application | ELISA |
| Target Name | ANP / Atrial Natriuretic Peptide |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm |
| Sensitivity | 6.7 pg/ml |
| Sample Type | Serum, plasma, cell culture and tissue extract |
| Standard Range | 7.8 - 2000 pg/ml |
| Sample Volume | 50 µl |
| Alternate Names | Natriuretic peptides A; ANF; Atriopeptin II; RATANF; Prepronatriodilatin; ANP; Atrial natriuretic peptide; Atriopeptin III; Pnd; Atriopeptin I |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Nppa |
| Gene Full Name | natriuretic peptide A |
| Background | The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1. [provided by RefSeq, Oct 2015] |
| Function | Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity). [UniProt] |
| Highlight | Related products: Atrial Natriuretic Peptide antibodies; Atrial Natriuretic Peptide ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| PTM | Cleaved by CORIN upon secretion to produce the functional hormone. Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity. |
| Title | Download Link |
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| ARG81128 Rat Atrial Natriuretic Peptide (ANP) ELISA Kit User manual |
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