ARG80908
Rat MIP-1 alpha ELISA kit
Rat MIP-1 alpha ELISA kit for ELISA and Rat
Immune System kit
Overview
| Product Description | ARG80908 Rat MIP-1 alpha ELISA kit is a Enzyme Immunoassay kit for the quantification of Rat MIP-1 alpha in Serum, Plasma, Cell culture supernatants |
|---|---|
| Tested Reactivity | Rat |
| Tested Application | ELISA |
| Specificity | No significant cross-reactivity or interference with MIP-1β, MIP-1γ, RANTES. |
| Target Name | CCL3 / MIP1 alpha |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm |
| Sensitivity | 0.95 pg/ml |
| Sample Type | Serum, Plasma, Cell culture supernatants |
| Standard Range | 1.95 - 125 pg/ml |
| Sample Volume | 100 µl |
| Precision | CV: <10% |
| Alternate Names | MIP-1-alpha; SIS-beta; PAT 464.1; Tonsillar lymphocyte LD78 alpha protein; G0/G1 switch regulatory protein 19-1; Small-inducible cytokine A3; C-C motif chemokine 3; LD78-alpha; 4-69; Macrophage inflammatory protein 1-alpha; MIP1A; SCYA3; G0S19-1; LD78ALPHA |
Application Instructions
| Assay Time | 4 hours |
|---|
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | Ccl3 |
|---|---|
| Gene Full Name | chemokine (C-C motif) ligand 3 |
| Background | CCL3 protein also known as macrophage inflammatory protein 1 alpha (MIP-1 alpha), is a small inducible cytokine with inflammatory and chemokinetic properties. It plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. CCL3 is one of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant CCL3 (MIP-1 alpha) induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). [modified from RefSeq 2010 and UniProtKB] |
| Function | Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin. [UniProt] |
| Highlight | Related products: Rat MIP1 alpha ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Research Area | Immune System kit |
| PTM | N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells. |
| Title | Download Link |
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| ARG80908 Rat MIP-1 alpha ELISA kit User's manual |
 Download
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