ARG82625

Rat MMP3 ELISA Kit

Rat MMP3 ELISA Kit for ELISA and Rat

Overview

Product Description ARG82625 Rat MMP3 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rat MMP3 in serum and plasma.
Tested Reactivity Rat
Tested Application ELISA
Specificity The following recombinant Rat proteins were tested and exhibited no cross-reactivity or interference: ApoAI, BMP1, BMP2, BMP3, BMP4, BMP7, CRP, HGF, HSP27, IL1 alpha, IL1 RI, IL1 beta, IL1RA, IL2, IL4, IL5, IL6, IL8, IL10, IL12, IL13, IL15, IL17C, IL21, IL23, IFN gamma, MMP2, sIL2R, sIL6R, PDGF, PLA2G7, prolactin, TGF beta 1, TGF beta 2, TGF beta 3, TLR1, TLR2, TLR3, TNF alpha, TNF RI, TNF RII and VEGF.
Target Name MMP3
Conjugation Note Read at 450 nm.
Sensitivity 12.5 pg/ml
Sample Type Serum and plasma.
Standard Range 25 - 1600 pg/ml
Sample Volume 100 µl
Precision Intra-Assay CV: < 10%
Inter-Assay CV: < 10%
Alternate Names Transin-1; CHDS6; EC 3.4.24.17; SL-1; STMY1; Matrix metalloproteinase-3; STR1; STMY; MMP-3; Stromelysin-1

Application Instructions

Assay Time ~ 2.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol MMP3
Gene Full Name matrix metallopeptidase 3
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Function Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. [UniProt]
Cellular Localization Secreted, extracellular space, extracellular matrix. [UniProt]
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Title Download Link
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