ARG80935

Rat Prorenin / Renin ELISA Kit

Rat Prorenin / Renin ELISA Kit for ELISA and Rat

Cell Biology and Cellular Response kit

Overview

Product Description ARG80935 Rat Prorenin / Renin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rat Prorenin / Renin in plasma, serum or cell culture supernatants.
Tested Reactivity Rat
Tested Application ELISA
Target Name Prorenin / Renin
Conjugation HRP
Detection Range 0.1 - 100 ng/ml
Sample Type plasma, serum or cell culture supernatants
Sample Volume 100 μl
Alternate Names EC 3.4.23.15; Angiotensinogenase; HNFJ2; Renin

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol Ren
Gene Full Name renin
Background Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]
Function Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. [UniProt]
Highlight Related products:
Prorenin ELISA Kits;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
Research Area Cell Biology and Cellular Response kit
Title Download Link
ARG80935 Rat Prorenin / Renin ELISA Kit User's manual download icon Download