ARG30274

SOD1 and SOD2 Antibody Duo

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Component

Cat No Component Name Host clonality Reactivity Application Package
ARG64241 anti-SOD1 antibody Goat pAb Hu, Ms ICC/IF, WB 50 μg
ARG54937 anti-SOD2 antibody Rabbit pAb Hu, Ms, Rat ICC/IF, IHC-P, IHC-Fr, WB 50 μl

Overview

Product Description

Superoxide Dismutases (SODs, including SOD1 and SOD2) are enzymes that alternately catalyzes the dismutation of superoxide radicals into less damaging molecular oxygen or hydrogen peroxide. The overproduction of superoxide radicals can cause severe tissue and cell damages. SOD enzymes deal with the superoxide radical by alternately adding or removing an electron from the superoxide molecules it encounters, thus changing the O2− into one of two less damaging species: either molecular oxygen (O2) or hydrogen peroxide (H2O2). SOD1 and SOD2 became the most important antioxidant defense systems in almost all living things exposed to oxygen.

Fukui and Bao. 2010. Free Rad Biol and Med 6: 821-830
Nojima et al. 2015. Plos One 25(10)

Target Name SOD1 and SOD2
Alternate Names SOD1 and SOD2 antibody; Superoxide dismutase 1 and Superoxide dismutase 2 antibody; SOD2 antibody; SOD1 antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Specific References

Fe3O4 Nanozymes Improve Neuroblast Differentiation and Blood-Brain Barrier Integrity of the Hippocampal Dentate Gyrus in D-Galactose-Induced Aged Mice

ARG54937: WB / Mouse

Zihao Xia et al.
International Journal o f Molecular Sciences,  (2022)

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Dietary Fe 3 O 4 Nanozymes Prevent the Injury of Neurons and Blood-Brain Barrier Integrity from Cerebral Ischemic Stroke.

ARG54937: WB / Mouse

Bing Chun Yan et al.
ACS Biomater Sci Eng.,  (2021)

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The antiepileptic drug levetiracetam promotes neuroblast differentiation and expression of superoxide dismutase in the mouse hippocampal dentate gyrus via PI3K/Akt signalling.

ARG54937: WB / Mouse

Yan Bing-Chun et al.
Neurosci Lett.,  (2018)

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Topiramate Improves Neuroblast Differentiation of Hippocampal Dentate Gyrus in the D-Galactose-Induced Aging Mice via Its Antioxidant Effects.

ARG54937: WB/IHC-F / Mouse

Shen H et al.
Cell Mol Neurobiol.,  (2016)

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