ARG81165

UCHL1 ELISA Kit

UCHL1 ELISA Kit for ELISA and Human,Mouse,Rat,Horse,Cow,Pig,Chicken

Overview

Product Description ARG81165 UCHL1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of UCHL1 in plasma, serum, CSF, urine and tissue extracts.
Tested Reactivity Hu, Ms, Rat, Chk, Cow, Hrs, Pig
Tested Application ELISA
Target Name UCHL1 / PGP9.5
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm
Sample Type Plasma, serum, CSF, urine and tissue extracts.
Standard Range 78.125 - 5000 pg/ml
Sample Volume 50 µl
Alternate Names PGP95; UCH-L1; PGP9.5; PARK5; Ubiquitin thioesterase L1; HEL-117; Neuron cytoplasmic protein 9.5; Uch-L1; EC 6.-.-.-; PGP 9.5; Ubiquitin carboxyl-terminal hydrolase isozyme L1; NDGOA; EC 3.4.19.12

Application Instructions

Assay Time ~ 6 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 22223 Mouse UCHL1

GeneID: 29545 Rat UCHL1

GeneID: 396637 Pig UCHL1

Gene Symbol UCHL1
Gene Full Name ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Background The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]
Function Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity. [UniProt]
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Calculated MW 24 kDa
PTM O-glycosylated.
Title Download Link
ARG81165 UCHL1 ELISA Kit User's manual download icon Download