ARG82182

alpha Mannosidase Activity Assay Kit (Colorimetric)

alpha Mannosidase Activity Assay Kit (Colorimetric) for Functional study and Human,Mouse,Rat,All species

Overview

Product Description ARG82182 alpha Mannosidase Activity Assay Kit (Colorimetric) can be used to measure alpha Mannosidase activity in serum, plasma, tissue and cell culture supernatants.
Tested Reactivity Hu, Ms, Rat, All
Tested Application FuncSt
Target Name alpha Mannosidase
Conjugation Note Read at 405 nm
Sensitivity 1 U/L
Detection Range 1 - 250 U/L
Sample Type serum, plasma, tissue and cell culture supernatants
Sample Volume 10 µl
Alternate Names Mannosidase alpha class 2A member 1; AMan II; Golgi alpha-mannosidase II; MANA2; Alpha-mannosidase 2; Man II; GOLIM7; Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase; MANII; EC 3.2.1.114

Application Instructions

Application Note Please note that this kit does not include a microplate.
Assay Time 10 min

Properties

Form Liquid
Storage Instruction Store the kit at 2-8°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 17158 Mouse MAN2A1

GeneID: 25478 Rat MAN2A1

GeneID: 4124 Human MAN2A1

Gene Symbol MAN2A1
Gene Full Name mannosidase, alpha, class 2A, member 1
Background This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq, Dec 2013]
Function Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. [UniProt]
Cellular Localization Golgi apparatus membrane; Single-pass type II membrane protein. [UniProt]
Title Download Link
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