ARG44624
anti-A RAF antibody
anti-A RAF antibody for Immunoprecipitation and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes A RAF |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IP |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | A RAF |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | ARAF; A-Raf Proto-Oncogene, Serine/Threonine Kinase; A-Raf; ARAF1; V-Raf Murine Sarcoma 3611 Viral Oncogene Homolog 1; Serine/Threonine-Protein Kinase A-Raf; Proto-Oncogene A-Raf-1; Proto-Oncogene Pks; EC 2.7.11.1; PKS2; V-Raf Murine Sarcoma 3611 Viral Oncogene-Like Protein; A-Raf Proto-Oncogene Serine/Threonine-Protein Kinase; Ras-Binding Protein DA-Raf; Proto-Oncogene A-Raf; Oncogene ARAF1; EC 2.7.11; RAFA1; PKS |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P10398 Human Serine/threonine-protein kinase A-Raf |
|---|---|
| Gene Symbol | ARAF |
| Gene Full Name | A-Raf Proto-Oncogene, Serine/Threonine Kinase |
| Background | Enables protein serine/threonine kinase activity. Involved in negative regulation of apoptotic process; regulation of TOR signaling; and regulation of cellular protein metabolic process. Predicted to be active in cytosol and mitochondrion. Biomarker of high grade glioma. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Phosphorylates PFKFB2. [UniProt] |
| Calculated MW | 68 kDa |
| PTM | Phosphoprotein. [UniProt] |
