ARG58247

anti-AADAC antibody

anti-AADAC antibody for Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes AADAC
Tested Reactivity Hu, Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name AADAC
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 170-399 of Human AADAC (NP_001077.2).
Conjugation Un-conjugated
Alternate Names EC 3.1.1.3; CES5A1; Arylacetamide deacetylase; DAC

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control A549
Observed Size 46 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 13 Human AADAC

GeneID: 67758 Mouse AADAC

Swiss-port # P22760 Human Arylacetamide deacetylase

Swiss-port # Q99PG0 Mouse Arylacetamide deacetylase

Gene Symbol AADAC
Gene Full Name arylacetamide deacetylase
Background Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq, Jul 2008]
Function Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. [UniProt]
Cellular Localization Endoplasmic reticulum membrane, Single-pass type II membrane protein, Microsome membrane. [UniProt]
Calculated MW 46 kDa
PTM Glycosylation is required for enzyme activity. [UniProt]