ARG44363
anti-AASS antibody
anti-AASS antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes AASS |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AASS |
| Antigen Species | Human |
| Immunogen | Human AASS recombinant fusion protein (a.a. sequence: 480-600). |
| Conjugation | Un-conjugated |
| Alternate Names | AASS; Aminoadipate-Semialdehyde Synthase; LORSDH; LKRSDH; Alpha-Aminoadipic Semialdehyde Synthase, Mitochondrial; LKR/SDH; Lysine-Ketoglutarate Reductase /Saccharopine Dehydrogenase; Lysine Ketoglutarate Reductase/Saccharopine Dehydrogenase; Alpha-Aminoadipate Semialdehyde Synthase; Alpha-Aminoadipic Semialdehyde Synthase; Aminoadipic Semialdehyde Synthase; Lysine-2-Oxoglutarate Reductase |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.05% Proclin300 and 50% Glycerol. |
| Preservative | 0.05% Proclin300 |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | AASS |
| Gene Full Name | Aminoadipate-Semialdehyde Synthase |
| Background | This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. |
| Function | Bifunctional enzyme that catalyzes the first two steps in lysine degradation. |
| Cellular Localization | Mitochondrion |
| Calculated MW | 102 kDa |
| PTM | Acetylation |
