ARG57118
anti-ACAT1 antibody [15E5]
anti-ACAT1 antibody [15E5] for ICC/IF,Western blot and Human
Overview
Product Description | Mouse Monoclonal antibody [15E5] recognizes ACAT1 |
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Tested Reactivity | Hu |
Tested Application | ICC/IF, WB |
Host | Mouse |
Clonality | Monoclonal |
Clone | 15E5 |
Isotype | IgG1, kappa |
Target Name | ACAT1 |
Antigen Species | Human |
Immunogen | Recombinant fragment around aa. 34-427 of Human ACAT1 |
Conjugation | Un-conjugated |
Alternate Names | EC 2.3.1.9; Acetoacetyl-CoA thiolase; MAT; T2; ACAT; THIL; Acetyl-CoA acetyltransferase, mitochondrial |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purification with Protein A. |
Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
Preservative | 0.02% Sodium azide |
Stabilizer | 10% Glycerol |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # P24752 Human Acetyl-CoA acetyltransferase, mitochondrial |
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Gene Symbol | ACAT1 |
Gene Full Name | acetyl-CoA acetyltransferase 1 |
Background | This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009] |
Function | Plays a major role in ketone body metabolism. [UniProt] |
Calculated MW | 45 kDa |
PTM | Succinylation at Lys-268, adjacent to a coenzyme A binding site. Desuccinylated by SIRT5 (By similarity). |