ARG66165
anti-ACOT11 antibody
anti-ACOT11 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ACOT11 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ACOT11 |
| Antigen Species | Human |
| Immunogen | Fusion protein of Human ACOT11. |
| Conjugation | Un-conjugated |
| Alternate Names | Adipose-associated thioesterase; STARD14; Acyl-CoA thioester hydrolase 11; THEM1; BFIT; THEA; Acyl-CoA thioesterase 11; Acyl-coenzyme A thioesterase 11; Brown fat-inducible thioesterase; EC 3.1.2.- |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | WB: Human fetal kidney and fetal lung. IHC-P: Human cervical cancer and thyroid cancer. |
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| Observed Size | ~ 68 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 40% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ACOT11 |
| Gene Full Name | acyl-CoA thioesterase 11 |
| Background | This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010] |
| Function | Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 68 kDa |
