ARG43625
anti-ADAM28 antibody
anti-ADAM28 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ADAM28 |
|---|---|
| Tested Reactivity | Rat |
| Predict Reactivity | Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ADAM28 |
| Antigen Species | Rat |
| Immunogen | Recombinant fragment corresponding to a.a. K26-K195 of Rat ADAM28. |
| Conjugation | Un-conjugated |
| Protein Full Name | Disintegrin and metalloproteinase domain-containing protein 28 |
| Alternate Names | Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; eMDC II; EC 3.4.24.-; MDC-L; MDCL; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L; Disintegrin and metalloproteinase domain-containing protein 28; eMDCII; ADAM 28 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 87, 61 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | Adam28 |
|---|---|
| Gene Full Name | ADAM metallopeptidase domain 28 |
| Background | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| Function | May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation. [UniProt] |
| Cellular Localization | Cell membrane; Membrane; Secreted |
| Calculated MW | 87 kDa |
| PTM | Pro-domain removal and maturation may be, at least in part, autocatalytic. [UniProt] |
