ARG56975

anti-ADRM1 antibody [34C2]

anti-ADRM1 antibody [34C2] for Western blot,Flow cytometry and Human

Overview

Product Description Mouse Monoclonal antibody [34C2] recognizes ADRM1
Tested Reactivity Hu
Tested Application FACS, WB
Host Mouse
Clonality Monoclonal
Clone 34C2
Isotype IgG2b, kappa
Target Name ADRM1
Antigen Species Human
Immunogen Recombinant fragment around aa. 1-407 of Human ADRM1.
Conjugation Un-conjugated
Alternate Names 110 kDa cell membrane glycoprotein; hRpn13; ARM1; ARM-1; Proteasomal ubiquitin receptor ADRM1; Gp110; Adhesion-regulating molecule 1; GP110; Rpn13 homolog; Proteasome regulatory particle non-ATPase 13

Application Instructions

Application Suggestion
Tested Application Dilution
FACSAssay-dependent
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 10% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 11047 Human ADRM1

Swiss-port # Q16186 Human Proteasomal ubiquitin receptor ADRM1

Gene Symbol ADRM1
Gene Full Name adhesion regulating molecule 1
Background This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Function Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. [UniProt]
Calculated MW 42 kDa