ARG65405

anti-AGPS antibody [AGPS-03]

anti-AGPS antibody [AGPS-03] for Flow cytometry,Western blot and Human

Neuroscience antibody

Overview

Product Description Mouse Monoclonal antibody [AGPS-03] recognizes AGPS
Tested Reactivity Hu
Tested Application FACS, WB
Specificity The clone AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an peroxisomal enzyme important for lipid biosynthesis.
Host Mouse
Clonality Monoclonal
Clone AGPS-03
Isotype IgG2a
Target Name AGPS
Antigen Species Human
Immunogen recombinant human AGPS (amino acids 158-384)
Conjugation Un-conjugated
Alternate Names ADHAPS; ALDHPSY; EC 2.5.1.26; ADAS; ADAP-S; Alkyldihydroxyacetonephosphate synthase, peroxisomal; Alkyl-DHAP synthase; Alkylglycerone-phosphate synthase; ADPS; Aging-associated gene 5 protein

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1 - 4 µg/ml
WBAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from cell culture supernatant by protein-A affinity chromatography.
Purity > 95% (by SDS-PAGE)
Buffer PBS (pH 7.4) and 15 mM Sodium azide
Preservative 15 mM Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 8540 Human AGPS

Swiss-port # O00116 Human Alkyldihydroxyacetonephosphate synthase, peroxisomal

Gene Symbol AGPS
Gene Full Name alkylglycerone phosphate synthase
Background AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.
Function Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. [UniProt]
Research Area Neuroscience antibody
Calculated MW 73 kDa