ARG65405
anti-AGPS antibody [AGPS-03]
anti-AGPS antibody [AGPS-03] for Flow cytometry,Western blot and Human
Neuroscience antibody
Overview
| Product Description | Mouse Monoclonal antibody [AGPS-03] recognizes AGPS |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, WB |
| Specificity | The clone AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an peroxisomal enzyme important for lipid biosynthesis. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | AGPS-03 |
| Isotype | IgG2a |
| Target Name | AGPS |
| Antigen Species | Human |
| Immunogen | recombinant human AGPS (amino acids 158-384) |
| Conjugation | Un-conjugated |
| Alternate Names | ADHAPS; ALDHPSY; EC 2.5.1.26; ADAS; ADAP-S; Alkyldihydroxyacetonephosphate synthase, peroxisomal; Alkyl-DHAP synthase; Alkylglycerone-phosphate synthase; ADPS; Aging-associated gene 5 protein |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from cell culture supernatant by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O00116 Human Alkyldihydroxyacetonephosphate synthase, peroxisomal |
|---|---|
| Gene Symbol | AGPS |
| Gene Full Name | alkylglycerone phosphate synthase |
| Background | AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse. |
| Function | Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids. [UniProt] |
| Research Area | Neuroscience antibody |
| Calculated MW | 73 kDa |
