ARG63765

anti-AGRP / Agouti related protein antibody

anti-AGRP / Agouti related protein antibody for IHC-Frozen sections and Human

Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes AGRP / Agouti related protein
Tested Reactivity Hu
Predict Reactivity Dog, Pig
Tested Application IHC-Fr
Specificity This antibody is expected to recognise both reported isoforms (as represented by NP_001129; NP_015531)
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name AGRP / Agouti related protein
Antigen Species Human
Immunogen CRKLGTAMNPCSRT
Conjugation Un-conjugated
Alternate Names Agouti-related protein; AGRT; ART; ASIP2

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-Fr0.05 - 0.1 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0) at 80°C for 30 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 181 Human AGRP

Swiss-port # O00253 Human Agouti-related protein

Background This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]
Research Area Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Calculated MW 14 kDa