ARG64140
anti-AGTR1 / AT1 antibody
anti-AGTR1 / AT1 antibody for Western blot and Human,Mouse
Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes AGTR1 / AT1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Specificity | All reported variants represent identical protein (NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1 and NP_114438.1). |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AGTR1 / AT1 |
| Antigen Species | Human |
| Immunogen | C-EIQKNKPRNDDIFK |
| Conjugation | Un-conjugated |
| Alternate Names | AT1AR; Angiotensin II type-1 receptor; AT1R; Type-1 angiotensin II receptor; AT1BR; AG2S; AT2R1; HAT1R; AT1; AGTR1B; AT1B |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012] |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody |
| Calculated MW | 41 kDa |
| PTM | C-terminal Ser or Thr residues may be phosphorylated. |
