ARG55353

anti-ALDH1A1 antibody

anti-ALDH1A1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cancer antibody; Developmental Biology antibody; Neuroscience antibody

Overview

Product Description Mouse Monoclonal antibody recognizes ALDH1A1
Tested Reactivity Hu
Tested Application ICC/IF, IHC-P, WB
Host Mouse
Clonality Monoclonal
Clone 152CT1.2.2
Isotype IgG1
Target Name ALDH1A1
Antigen Species Human
Immunogen Human ALDH1A1 recombinant protein.
Conjugation Un-conjugated
Alternate Names HEL-S-53e; RalDH1; Aldehyde dehydrogenase family 1 member A1; Retinal dehydrogenase 1; HEL-9; RALDH 1; ALDH1; Aldehyde dehydrogenase, cytosolic; ALDH11; EC 1.2.1.36; RALDH1; HEL12; PUMB1; ALHDII; ALDC; ALDH-E1

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:10 - 1:50
IHC-P1:50 - 1:100
WB1:500 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control K562

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 216 Human ALDH1A1

Swiss-port # P00352 Human Retinal dehydrogenase 1

Gene Symbol ALDH1A1
Gene Full Name aldehyde dehydrogenase 1 family, member A1
Background The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]
Function Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity). [UniProt]
Cellular Localization Cytoplasm.
Research Area Cancer antibody; Developmental Biology antibody; Neuroscience antibody
Calculated MW 55 kDa
PTM The N-terminus is blocked most probably by acetylation.