ARG57310

anti-ALDH1A1 antibody

anti-ALDH1A1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes ALDH1A1
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ALDH1A1
Antigen Species Human
Immunogen Recombinant Protein of Human ALDH1A1.
Conjugation Un-conjugated
Alternate Names HEL-S-53e; RalDH1; Aldehyde dehydrogenase family 1 member A1; Retinal dehydrogenase 1; HEL-9; RALDH 1; ALDH1; Aldehyde dehydrogenase, cytosolic; ALDH11; EC 1.2.1.36; RALDH1; HEL12; PUMB1; ALHDII; ALDC; ALDH-E1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control K562

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 11668 Mouse ALDH1A1

GeneID: 216 Human ALDH1A1

GeneID: 24188 Rat ALDH1A1

Gene Symbol ALDH1A1
Gene Full Name aldehyde dehydrogenase 1 family, member A1
Background The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]
Function Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity). [UniProt]
Calculated MW 55 kDa
PTM The N-terminus is blocked most probably by acetylation.