ARG58664

anti-ALDH1A2 antibody

anti-ALDH1A2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes ALDH1A2
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ALDH1A2
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-180 of Human ALDH1A2 (NP_733797.1).
Conjugation Un-conjugated
Alternate Names RALDH; RALDH2-T; RalDH2; Retinal dehydrogenase 2; RALDH(II); RALDH 2; RALDH2; EC 1.2.1.36; II; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control 293T
Observed Size 57 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 116676 Rat ALDH1A2

GeneID: 19378 Mouse ALDH1A2

GeneID: 8854 Human ALDH1A2

Gene Symbol ALDH1A2
Gene Full Name aldehyde dehydrogenase 1 family, member A2
Background This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]
Function Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity). [UniProt]
Cellular Localization Cytoplasm. [UniProt]
Calculated MW 57 kDa