ARG54807
anti-ALDH1A3 antibody
anti-ALDH1A3 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Publication1
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ALDH1A3 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ALDH1A3 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 24-51 (N-terminus) of Human ALDH1A3. |
| Conjugation | Un-conjugated |
| Alternate Names | RALDH-3; EC 1.2.1.5; Aldehyde dehydrogenase 6; ALDH6; RALDH3; MCOP8; RalDH3; ALDH1A6; Aldehyde dehydrogenase family 1 member A3; Retinaldehyde dehydrogenase 3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | 293 |
Properties
| Form | Liquid |
|---|---|
| Purification | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P47895 Human Aldehyde dehydrogenase family 1 member A3 Swiss-port # Q9JHW9 Mouse Aldehyde dehydrogenase family 1 member A3 |
|---|---|
| Gene Symbol | ALDH1A3 |
| Gene Full Name | aldehyde dehydrogenase 1 family, member A3 |
| Background | This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
| Function | Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system (By similarity). [UniProt] |
| Cellular Localization | Cytoplasm. |
| Research Area | Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 56 kDa |
Specific References
ALDH1A3 Accelerates Pancreatic Cancer Metastasis by Promoting Glucose Metabolism.
IHC-P / Human
