ARG65260

anti-ALDH3A1 antibody

anti-ALDH3A1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes ALDH3A1
Tested Reactivity Hu, Ms
Tested Application IHC-P, WB
Specificity Reported variants represent identical protein: NP_001128639.1, NP_000682.3, NP_001128640.1
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name ALDH3A1
Antigen Species Human
Immunogen C-RYPPSPAKMTQH
Conjugation Un-conjugated
Alternate Names Aldehyde dehydrogenase, dimeric NADP-preferring; EC 1.2.1.5; ALDHIII; Aldehyde dehydrogenase family 3 member A1; Aldehyde dehydrogenase 3; ALDH3

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P3 - 5 µg/ml
WB0.01 - 0.03 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 11670 Mouse ALDH3A1

GeneID: 218 Human ALDH3A1

Swiss-port # P30838 Human Aldehyde dehydrogenase, dimeric NADP-preferring

Swiss-port # P47739 Mouse Aldehyde dehydrogenase, dimeric NADP-preferring

Background Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
Research Area Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Calculated MW 50 kDa