ARG57061
anti-ALDH5A1 antibody [17F5]
anti-ALDH5A1 antibody [17F5] for ICC/IF,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [17F5] recognizes ALDH5A1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 17F5 |
| Isotype | IgG2a, kappa |
| Target Name | ALDH5A1 |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 48-535 of Human ALDH5A1. |
| Conjugation | Un-conjugated |
| Alternate Names | SSDH; SSADH; NAD; +; Aldehyde dehydrogenase family 5 member A1; EC 1.2.1.24; Succinate-semialdehyde dehydrogenase, mitochondrial |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P51649 Human Succinate-semialdehyde dehydrogenase, mitochondrial |
|---|---|
| Gene Symbol | ALDH5A1 |
| Gene Full Name | aldehyde dehydrogenase 5 family, member A1 |
| Background | This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Function | Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). [UniProt] |
| Calculated MW | 57 kDa |
