ARG40438

anti-ALDH6A1 antibody

anti-ALDH6A1 antibody for Western blot,ICC/IF and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes ALDH6A1
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ALDH6A1
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 326-535 of Human ALDH6A1 (NP_005580.1).
Conjugation Un-conjugated
Alternate Names MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; EC 1.2.1.18; EC 1.2.1.27; MMSADHA

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control 22Rv1
Observed Size 58 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 104776 Mouse ALDH6A1

GeneID: 4329 Human ALDH6A1

GeneID: 81708 Rat ALDH6A1

Gene Symbol ALDH6A1
Gene Full Name aldehyde dehydrogenase 6 family, member A1
Background This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Function Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA. [UniProt]
Cellular Localization Mitochondrion. [UniProt]
Calculated MW 58 kDa