ARG40178
anti-ALKBH5 antibody
anti-ALKBH5 antibody for Flow cytometry,Western blot and Human
Overview
Product Description | Rabbit Polyclonal antibody recognizes ALKBH5 |
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Tested Reactivity | Hu |
Tested Application | FACS, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | ALKBH5 |
Antigen Species | Human |
Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 302-330 of Human ALKBH5. |
Conjugation | Un-conjugated |
Alternate Names | OFOXD1; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5; Alkylated DNA repair protein alkB homolog 5; ABH5; OFOXD; EC 1.14.11.-; RNA demethylase ALKBH5 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | HeLa |
Properties
Form | Liquid |
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Purification | Purification with Protein A and immunogen peptide. |
Buffer | PBS and 0.09% (W/V) Sodium azide. |
Preservative | 0.09% (W/V) Sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8��C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | ALKBH5 |
Gene Full Name | AlkB family member 5, RNA demethylase |
Function | Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro). Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for spermatogenesis (By similarity). [UniProt] |
Cellular Localization | Nucleus speckle. [UniProt] |
Calculated MW | 44 kDa |