ARG40178

anti-ALKBH5 antibody

anti-ALKBH5 antibody for Flow cytometry,Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes ALKBH5
Tested Reactivity Hu
Tested Application FACS, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ALKBH5
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 302-330 of Human ALKBH5.
Conjugation Un-conjugated
Alternate Names OFOXD1; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5; Alkylated DNA repair protein alkB homolog 5; ABH5; OFOXD; EC 1.14.11.-; RNA demethylase ALKBH5

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:25
WB1:500
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HeLa

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8��C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 54890 Human ALKBH5

Swiss-port # Q6P6C2 Human RNA demethylase ALKBH5

Gene Symbol ALKBH5
Gene Full Name AlkB family member 5, RNA demethylase
Function Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro). Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for spermatogenesis (By similarity). [UniProt]
Cellular Localization Nucleus speckle. [UniProt]
Calculated MW 44 kDa