ARG11106

anti-AMH antibody [AMH69cc]

anti-AMH antibody [AMH69cc] for Chemiluminescence immunoassay,ELISA,Purification,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody [AMH69cc] recognizes AMH
Tested Reactivity Hu
Tested Application CLIA, ELISA, IHC-P, Puri, WB
Specificity Mullerian hormone
Host Mouse
Clonality Monoclonal
Clone AMH69cc
Isotype IgG2b
Target Name AMH
Antigen Species Human
Immunogen Recombinant Human AMH.
Conjugation Un-conjugated
Alternate Names AMH; Muellerian-inhibiting substance; MIF; Anti-Muellerian hormone; Muellerian-inhibiting factor; MIS

Application Instructions

Application Suggestion
Tested Application Dilution
CLIAAssay-dependent
ELISAAssay-dependent
IHC-PAssay-dependent
PuriAssay-dependent
WBAssay-dependent
Application Note Sandwich ELISA (Capture antibody - Detection antibody): ARG11106 - ARG11105

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A.
Buffer 50 mM Sodium citrate (pH 6.5), 150 mM NaCl and 0.09% Sodium azide.
Preservative 0.09% Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 268 Human AMH

Swiss-port # P03971 Human Muellerian-inhibiting factor

Gene Symbol AMH
Gene Full Name anti-Mullerian hormone
Background This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]
Function This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 59 kDa