ARG40888
anti-ANP32A / PHAP1 antibody
anti-ANP32A / PHAP1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ANP32A / PHAP1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ANP32A / PHAP1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-170 of Human ANP32A (NP_006296.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Putative HLA-DR-associated protein I; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; Mapmodulin; pp32; PHAPI; C15orf1; PP32; I1PP2A; PHAP1; Acidic nuclear phosphoprotein pp32; LANP; Acidic leucine-rich nuclear phosphoprotein 32 family member A; HPPCn; MAPM; Leucine-rich acidic nuclear protein |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Raji | ||||||||
| Observed Size | 28 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ANP32A |
| Gene Full Name | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| Function | Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression. [UniProt] |
| Cellular Localization | Cytoplasm, Endoplasmic reticulum, Nucleus. [UniProt] |
| Calculated MW | 29 kDa |
| PTM | Phosphorylated on serine residues. The N-terminus is blocked. Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group (By similarity). [UniProt] |
