ARG57389
anti-AP1M1 antibody
anti-AP1M1 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes AP1M1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | AP1M1 |
| Antigen Species | Human |
| Immunogen | Recombinant Protein of Human AP1M1. |
| Conjugation | Un-conjugated |
| Alternate Names | MU-1A; Mu-adaptin 1; Adaptor-related protein complex 1 subunit mu-1; Clathrin coat-associated protein AP47; Mu1A-adaptin; Clathrin assembly protein complex 1 mu-1 medium chain 1; AP47; CLTNM; AP-1 complex subunit mu-1; Clathrin coat assembly protein AP47; Golgi adaptor HA1/AP1 adaptin mu-1 subunit; Adaptor protein complex AP-1 subunit mu-1; CLAPM2; AP-mu chain family member mu1A |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse brain |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | AP1M1 |
| Gene Full Name | adaptor-related protein complex 1, mu 1 subunit |
| Background | The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. [UniProt] |
| Calculated MW | 49 kDa |
| PTM | Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals. |
