ARG44777
anti-AREL1 antibody
anti-AREL1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes AREL1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Target Name | AREL1 |
| Antigen Species | Human |
| Epitope | FDIIVLSEDE KNIVERNVST SGVSIYFEAY LYNATNCSST PWHLPPMHMT SSQRRPSTAV DEEDEDSPSE CHTPEKVKKP |
| Conjugation | Un-conjugated |
| Alternate Names | AREL1; Apoptosis Resistant E3 Ubiquitin Protein Ligase 1; KIAA0317; FIEL1; Apoptosis-Resistant HECT-Type E3 Ubiquitin Transferase 1; Apoptosis-Resistant E3 Ubiquitin Protein Ligase 1; Fibrosis-Inducing E3 Ligase 1; EC 2.3.2.26 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | AREL1 |
|---|---|
| Gene Full Name | Apoptosis Resistant E3 Ubiquitin Protein Ligase 1 |
| Background | Enables ubiquitin-protein transferase activity. Involved in negative regulation of apoptotic process; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Modulates pulmonary inflammation by targeting SOCS2 for ubiquitination and subsequent degradation by the proteasome. [Uniprot] |
| PTM | Ubl conjugation. [Uniprot] |
