ARG65768
anti-ARHGEF5 antibody
anti-ARHGEF5 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ARHGEF5 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ARHGEF5 |
| Antigen Species | Human |
| Immunogen | Fusion protein of Human ARHGEF5 (NP_005426.2) |
| Conjugation | Un-conjugated |
| Alternate Names | P60; TIM1; Oncogene TIM; Rho guanine nucleotide exchange factor 5; TIM; GEF5; Ephexin-3; p60 TIM; Transforming immortalized mammary oncogene; Guanine nucleotide regulatory protein TIM |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 40% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q12774 Human Rho guanine nucleotide exchange factor 5 |
|---|---|
| Gene Symbol | ARHGEF5 |
| Gene Full Name | Rho guanine nucleotide exchange factor (GEF) 5 |
| Background | Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008] |
| Calculated MW | 177 kDa |
| PTM | Activation of SRC induces tyrosine phosphorylation of ARHGEF5. |
