ARG22622

anti-ATG10 antibody

anti-ATG10 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes ATG10
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ATG10
Antigen Species Human
Immunogen Synthetic peptide around the center region of Human ATG10.
Conjugation Un-conjugated
Alternate Names EC 6.3.2.-; Autophagy-related protein 10; APG10-like; APG10; Ubiquitin-like-conjugating enzyme ATG10; APG10L; pp12616

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS, 0.09% Sodium azide and 50% Glycerol.
Preservative 0.09% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 83734 Human ATG10

Swiss-port # Q9H0Y0 Human Ubiquitin-like-conjugating enzyme ATG10

Gene Symbol ATG10
Gene Full Name autophagy related 10
Background Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]
Function E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis. [UniProt]
Calculated MW 25 kDa