ARG57844
anti-ATIC antibody
anti-ATIC antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ATIC |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ATIC |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human ATIC. |
| Conjugation | Un-conjugated |
| Alternate Names | Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; AICAR transformylase; ATIC; Inosinicase; EC 2.1.2.3; IMPCHASE; AICARFT; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; AICAR; EC 3.5.4.10; PURH; HEL-S-70p; IMP synthase |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HT-29 | ||||
| Observed Size | ~ 63 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P31939 Human Bifunctional purine biosynthesis protein PURH |
|---|---|
| Gene Symbol | ATIC |
| Gene Full Name | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| Background | This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009] |
| Function | Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis. [UniProt] |
| Calculated MW | 65 kDa |
