ARG57844

anti-ATIC antibody

anti-ATIC antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes ATIC
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ATIC
Antigen Species Human
Immunogen Recombinant protein of Human ATIC.
Conjugation Un-conjugated
Alternate Names Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; AICAR transformylase; ATIC; Inosinicase; EC 2.1.2.3; IMPCHASE; AICARFT; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; AICAR; EC 3.5.4.10; PURH; HEL-S-70p; IMP synthase

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HT-29
Observed Size ~ 63 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 471 Human ATIC

Swiss-port # P31939 Human Bifunctional purine biosynthesis protein PURH

Gene Symbol ATIC
Gene Full Name 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Background This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]
Function Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis. [UniProt]
Calculated MW 65 kDa