ARG54646

anti-ATP11B antibody

anti-ATP11B antibody for ELISA,ICC/IF,Western blot and Human,Mouse

Metabolism antibody; Signaling Transduction antibody

Overview

Product Description

Rabbit Polyclonal antibody recognizes ATP11B

Tested Reactivity Hu, Ms
Tested Application ELISA, ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ATP11B
Antigen Species Human
Immunogen Synthetic peptide (19 aa) within aa. 290-340 of Human ATP11B protein.
Conjugation Un-conjugated
Alternate Names ATPIF; Probable phospholipid-transporting ATPase IF; ATPase IR; ATPase class VI type 11B; ATPIR; EC 3.6.3.1; P4-ATPase flippase complex alpha subunit ATP11B

Application Instructions

Application Suggestion
Tested Application Dilution
ELISAAssay-dependent
ICC/IF10 μg/ml - 20 μg/ml
WB1 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control K562 Cell Lysate

Properties

Form Liquid
Purification Immunogen affinity purified
Buffer PBS and 0.02% Sodium azide
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 23200 Human ATP11B

Swiss-port # Q9Y2G3 Human Probable phospholipid-transporting ATPase IF

Gene Symbol ATP11B
Gene Full Name ATPase, class VI, type 11B
Background ATP11B Antibody: ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
Research Area Metabolism antibody; Signaling Transduction antibody
Calculated MW 134 kDa