ARG44999
anti-ATP1A3 antibody
anti-ATP1A3 antibody for ELISA,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ATP1A3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ATP1A3 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide (a.a 444-477) from human ATP1A3. |
| Conjugation | Un-conjugated |
| Alternate Names | ATP1A3; ATPase Na+/K+ Transporting Subunit Alpha 3; Sodium/Potassium-Transporting ATPase Subunit Alpha-3; Sodium Pump Subunit Alpha-3; Sodium-Potassium ATPase Catalytic Subunit Alpha-3; ATPase, Na+/K+ Transporting, Alpha 3 Polypeptide; Na(+)/K(+) ATPase Alpha(III) Subunit; Na(+)/K(+) ATPase Alpha-3 Subunit; DYT12; Na+, K+ Activated Adenosine Triphosphatase Alpha Subunit; Sodium/Potassium-Transporting ATPase Alpha-3 Chain; Sodium-Potassium-ATPase, Alpha 3 Polypeptide; Na+/K+ ATPase 3; Dystonia 12; EC 7.2.2.13; EC 3.6.3.9; EC 3.6.3; ATP1A1; CAPOS; DEE99; AHC2; RDP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A Purified |
| Buffer | PBS and 0.09% Sodium azide |
| Preservative | 0.09% Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P13637 Human Sodium/potassium-transporting ATPase subunit alpha-3 |
|---|---|
| Gene Symbol | ATP1A3 |
| Gene Full Name | ATPase Na+/K+ Transporting Subunit Alpha 3 |
| Background | The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| Function | This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. [Uniprot] |
| Cellular Localization | Cell membrane, Membrane. [Uniprot] |
| Calculated MW | 112 kDa |
| PTM | Phosphoprotein. [Uniprot] |
