ARG65270
anti-ATP1B1 / Na+ K+ ATPase beta 1 antibody
anti-ATP1B1 / Na+ K+ ATPase beta 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Cancer antibody; Metabolism antibody; Signaling Transduction antibody
Overview
Product Description | Goat Polyclonal antibody recognizes ATP1B1 / Na+ K+ ATPase beta 1 |
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Tested Reactivity | Hu, Ms, Rat |
Predict Reactivity | Cow, Dog, Pig |
Tested Application | IHC-P, WB |
Specificity | This antibody is expected to recognize both reported isoforms (NP_001668.1; NP_001001787.1). |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | ATP1B1 / Na+ K+ ATPase beta 1 |
Antigen Species | Human |
Immunogen | C-KTEISFRPNDPKSYE |
Conjugation | Un-conjugated |
Alternate Names | Sodium/potassium-transporting ATPase subunit beta-1; Sodium/potassium-dependent ATPase subunit beta-1; ATP1B; Na+ K+ ATPase beta 1; Na K ATPase beta 1; sodium potassium ATPase beta 1; ATPase Na+ K+ beta 1; ATPase Na K beta 1; ATPase sodium potassium beta 1 |
Application Instructions
Application Suggestion |
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Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
Preservative | 0.02% Sodium azide |
Stabilizer | 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Background | The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010] |
Research Area | Cancer antibody; Metabolism antibody; Signaling Transduction antibody |
Calculated MW | 35 kDa |