ARG58326
anti-ATP6AP1 antibody
anti-ATP6AP1 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ATP6AP1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ATP6AP1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 90-390 of Human ATP6AP1 (NP_001174.2). |
| Conjugation | Un-conjugated |
| Alternate Names | V-ATPase S1 accessory protein; V-ATPase Ac45 subunit; ATP6IP1; VATPS1; Ac45; 16A; ATP6S1; V-ATPase subunit S1; XAP-3; Vacuolar proton pump subunit S1; XAP3; V-type proton ATPase subunit S1; Protein XAP-3; CF2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | PC-3 | ||||
| Observed Size | 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | ATP6AP1 |
| Gene Full Name | ATPase, H+ transporting, lysosomal accessory protein 1 |
| Background | This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013] |
| Function | Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. [UniProt] |
| Cellular Localization | Vacuole membrane, Single-pass membrane protein. [UniProt] |
| Calculated MW | 52 kDa |
| PTM | N-glycosylated. [UniProt] |
