ARG40206

anti-Annexin A1 antibody

anti-Annexin A1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Monkey,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes Annexin A1
Tested Reactivity Hu, Rat, Mk
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Annexin A1
Antigen Species Human
Immunogen Recombinant protein corresponding to A2-N346 of Human Annexin A1.
Conjugation Un-conjugated
Alternate Names ANX1; Calpactin II; Phospholipase A2 inhibitory protein; Chromobindin-9; LPC1; Annexin-1; Annexin A1; Lipocortin I; Annexin I; p35; Calpactin-2

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P0.5 - 1 µg/ml
WB0.1 - 0.5 µg/ml
Application Note IHC-P: Antigen Retrieval: By heat mediation.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA.
Preservative 0.05% Sodium azide
Stabilizer 5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 25380 Rat ANXA1

GeneID: 301 Human ANXA1

Swiss-port # P04083 Human Annexin A1

Swiss-port # P07150 Rat Annexin A1

Gene Symbol ANXA1
Gene Full Name annexin A1
Background This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
Function Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. [UniProt]
Cellular Localization Endosome; Nucleus; Plasma membrane; Secreted. [UniProt]
Calculated MW 39 kDa
PTM Phosphorylated by protein kinase C, EGFR and TRPM7 (PubMed:2457390, PubMed:15485879). Phosphorylated in response to EGF treatment (PubMed:2532504).

Sumoylated. [UniProt]