ARG55263

anti-Annexin A1 antibody

anti-Annexin A1 antibody for Western blot and Human,Mouse,Rat,Monkey

Signaling Transduction antibody

Overview

Product Description Mouse Monoclonal antibody recognizes Annexin A1
Tested Reactivity Hu, Ms, Rat, Mk
Tested Application WB
Specificity This antibody detects endogenous levels of Annexin A1 and does not cross-react with related proteins.
Host Mouse
Clonality Monoclonal
Isotype IgG1
Target Name Annexin A1
Antigen Species Human
Immunogen Purified recombinant fragment of Human Annexin A1 (NP_000691.1).
Conjugation Un-conjugated
Alternate Names ANX1; Calpactin II; Phospholipase A2 inhibitory protein; Chromobindin-9; LPC1; Annexin-1; Annexin A1; Lipocortin I; Annexin I; p35; Calpactin-2

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.4), 0.03% Proclin 300 and 50% Glycerol
Preservative 0.03% Proclin 300
Stabilizer 50% Glycerol
Concentration 4.85 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 16952 Mouse ANXA1

GeneID: 25380 Rat ANXA1

GeneID: 301 Human ANXA1

Gene Symbol ANXA1
Gene Full Name annexin A1
Background This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
Function Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. [UniProt]
Cellular Localization Nucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. [UniProt]
Research Area Signaling Transduction antibody
Calculated MW 39 kDa
PTM Phosphorylated by protein kinase C, EGFR and TRPM7 (PubMed:2457390, PubMed:15485879). Phosphorylated in response to EGF treatment (PubMed:2532504).
Sumoylated.